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Senti Biosciences Inc(原名:Dynamics Special Purpose Corp.)是一家臨床前生物技術公司。該公司正在開發利用它的基因電路平台技術設計的細胞和基因療法,以治癒疾病。該公司的先進的基因電路候選產品針對用於腫瘤學的同種異體CAR-NK細胞。該公司的臨床前階段候選產品包括SENTI-202、SENTI-301和SENTI-401。它正在開發它的SENTI-202候選產品作為邏輯門控(OR+NOT)同種異體CAR-NK細胞療法,旨在靶向和消除急性髓性白血病(AML)細胞,同時保留健康的骨髓。該公司的SENTI-301候選產品是一種多臂同種異體CAR-NK細胞療法,正在開髮用於治療肝細胞癌(HCC)。該公司的SENTI-401候選產品是一種邏輯門控同種異體CAR-NK細胞療法,它正在開發以靶向和消除結腸直腸癌(CRC)細胞。基因電路平台是它的技術平台。
名稱 | 年齡 | 成立於 | 主旨 |
---|---|---|---|
Martin Fussenegger | - | - | Member of Scientific Advisory Board |
Michael D. Varney | 65 | 2021 | Member of Scientific Advisory Board |
James J. Collins | 57 | 2021 | Scientific Co-Founder, Chairperson of Scientific Advisory Board & Independent Director |
Robin G. Taylor | - | 2021 | Member of Scientific Advisory Board |
Michael Andreeff | - | - | Member of Scientific Advisory Board |
Lawrence Fong | - | - | Member of Scientific Advisory Board |
Edward T. Mathers | 63 | 2016 | Independent Director |
Michael Kalos | - | 2021 | Member of Scientific Advisory Board |
Timothy K. Lu | 42 | 2016 | Co-Founder, CEO, President & Director |
Omid C. Farokhzad | 54 | 2022 | Independent Director |
Ahmad Khalil | - | - | Member of Scientific Advisory Board |
Brenda G. Cooperstone | 58 | 2019 | Independent Director |
Wilson Wong | - | - | Scientific Co-Founder & Member of Scientific Advisory Board |
Susan D. Berland | 69 | 2021 | Senior Financial Executive & Independent Director |
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