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SAGE Therapeutics Inc是一家生物製藥公司。該公司專注於腦保健藥物的開發和商業化。該公司的產品ZULRESSO(brexanolone)CIV注射劑用於治療成人產後抑鬱症(PPD)。該公司擁有一系列其他候選產品,重點是調節兩個中樞神經系統(CNS)受體系統,即GABA和NMDA。該公司針對大腦疾病和失調,重點關註三個領域:抑鬱症、神經病學和神經精神病學。其另一個先進的候選產品是zuranolone (SAGE-217),這是一種針對某些情感障礙開發的口服化合物,包括重度抑鬱症(MDD)和PPD。Zuranolone是一種神經活性類固醇,是GABAA受體的正變構調節劑,靶向突觸和突觸外GABAA受體。該公司擁有一系列針對GABAA受體的其他化合物,包括SAGE-324。
名稱 | 年齡 | 成立於 | 主旨 |
---|---|---|---|
Barry E. Greene | 58 | 2020 | President, CEO & Director |
George S. Golumbeski | 64 | 2019 | Independent Director |
Elizabeth A. Barrett | 59 | 2019 | Independent Director |
Kevin P. Starr | 58 | 2011 | Independent Chairman |
Stephen Moss | - | - | Member of Scientific Advisory Board |
Scott Runyon | - | - | Member of Scientific Advisory Board |
A. Leslie Morrow | - | - | Member of Scientific Advisory Board |
Stephen F. Traynelis | - | - | Member of Scientific Advisory Board |
Michael A. Rogawski | - | - | Member of Scientific Advisory Board |
James M. Frates | 55 | 2014 | Independent Director |
Michael F. Cola | 62 | 2014 | Independent Director |
Charles Zorumski | - | - | Member of Scientific Advisory Board |
David H. Farb | - | - | Member of Scientific Advisory Board |
Donald Stein | - | - | Member of Scientific Advisory Board |
Jeffrey M. Jonas | 69 | 2013 | Outside Non-Employee Member of CNS Innovation Advisory Board & Director |
Christine Marx | - | - | Member of Scientific Advisory Board |
James E. Audia | 66 | - | Member of Scientific Advisory Board |
Geno J. Germano | 61 | 2016 | Independent Director |
Steven M. Paul | 72 | 2011 | Independent Director |
Jessica J. Federer | 40 | 2023 | Independent Director |
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